VivaBioCell S.p.A.

NANT001

NANT001 is an innovative automated, closed bioreactor system for cell therapy bioprocessing, evolved from manual cell culture principles but developed to overcome the challenges linked to traditional expansion methods. Together with its companion single-use cartridge, NANT001 bioreactor allows to cover all operations from cell seeding to expansion, sampling and harvest of multiple cell types.

Nant001 Bioreactor - outside

Nant001 Bioreactor - inside

AUTOMATED CULTURE RESULTS: QUALITY CELLS IN LESS TIME AT HIGHER YIELD

hAD-MSC (human Adipose-Derived Mesenchymal Stem Cells) cultures

Starting material 15 mL lipoaspirate
Expansion time ~5-6 days
Yield at harvest 60-90 million
Viability >97%

hBM-MSC (human Bone Marrow-Derived Mesenchymal Stem Cells) cultures

Starting material Bone Marrow cryo-preserved cells
Expansion time ~5-6 days
Yield at harvest 50-75 million
Viability >97%

SYSTEM FEATURES

Automation

Safety

Flexibility

Technical Specifications

Core technology
  • Liquid lens-based autofocus microscopic imaging
  • Tilt and shake motors
  • Temperature control at 37°C (98,6 °F)
  • Peristaltic pump and five pinch-tube electrovalves for fluid pathways
  • pH estimation sensor
Cartridge
  • Single-use, fully disposable
  • Certified biocompatible parts
  • Includes reagents and waste bags
  • Harvest output up to 250 mL, collected in conical centrifuge bottle
  • Sterile, packaged in a ready-to-use kit
Software
  • Stand-alone, no PC required
  • Embedded cell confluency calculation software
Traceability
  • Barcode reader for user and cartridge
  • Data management with PDF final report
User interface Color touchscreen with intuitive GUI
Connectivity
  • Wireless remote process control
  • Ethernet port
Dimensions 500mm x 776mm x 580mm (19,7" x 30,6" x 22,8")
Power 350W, 100-240 VAC, 50/60Hz

Safety and compliance

Nant001 is a CE-certified machine for cell-based and cell-derived product manufacturing, compliant with the requirements demanded by Dir. 2006/42/EC, IEC 61010, IEC 61326, Eudralex Vol.4 and its Annex 11.

CONTACT US

Contact us at info@vivabiocell.it.